Publications

Les travaux scientifiques issus du registre

Publications avec comité de lecture

2024


Safety and efficacy of NOAC vs.VKA in patients treated by PCI: a retrospective study of the FRANCE PCI registry

Frontiers in Cardiovascular Medicine, January 2024


Conclusions

NOAC seems to have a better efficacy and safety profile than VKA. However, potential indication bias were found.


2023

The France PCI registry: Design, methodology and key findings

Archives of Cardiovascular Disease, September 2023


Conclusions 

This fully electronic, daily updated, high-quality, low-cost, national registry is sustainable, and is now expanding. Merging with medicoeconomic databases and nested randomized scientific studies are ongoing steps to expand its scientific potential.

Is the duration of dual antiplatelet therapy (DAPT) excessive in post-angioplasty in chronic coronary syndrome ? Data from the France-PCI registry (2014-2019)

Frontier in CV medecine, March 2023


Conclusions

Post-PCI DAPT duration in CCS was higher than international recommendations in the France PCI registry between 2014 and 2019. More than half of the angioplasty performed for CCS are followed by a DAPT > 12 months. Ischemic risk assessment influences the duration of DAPT. This risk is probably overestimated nowadays, leading to a prolongation of DAPT beyond the recommended durations, thus increasing the bleeding risk.

Prevalence, management and outcomes of percutaneous coronary intervention for coronary in-stent restenosis: Insights from the France PCI Registry

Cardiovascular Revascularization Medicine, February 2023


Conclusions

In a large all-comers registry, in-stent restenosis (ISR) PCI was not infrequent and associated with worse prognosis than non-ISR PCI. Further studies and technical improvements are warranted to improve the outcomes of ISR PCI


2022

Early survival after acute myocardial infarction with ST-segment elevation

What could be improved? Insights from France PCI French registry

Medicine (Baltimore). 2022 Sep 2


Conclusions

Most predictors of 30-day survival post-STEMI are unmodifiable, but outcomes might be improved by optimizing modifiable

factors, most importantly ischemic time and appropriate premedication.

Impact of the Lubrizol factory fire in Rouen on coronary events: A retrospective study from the France PCI registry

Archives of Cardiovascular Diseases, July 2022


Conclusions

On 26 September 2019, an industrial fire occurred in the Lubrizol factory in Rouen (France), exposing the population to the inhalation of many volatile toxic agents secondary to combustion. Our study did not find a significant effect of the Lubrizol factory fire on the incidence of acute coronary syndrome. Further studies are needed to investigate the impact of industrial accidents on air pollution and coronary events


Penetration of endocoronary imaging in France (data from France PCI): The French exception

Annales de cardiologie et d’angeiologie  (2022) 1−6


Conclusions

ICI techniques are exceptionally used in France in routine practice, in contrast to our European neighbors such as Swede or the United Kingdom. Obtaining reimbursement in certain recommended indications and participation in a national interventional cardiology registry with incentive practice indicators should improve this situation.

Indirect transfer to catheterization laboratory for ST elevation myocardial infarction is associated with mortality independent of system delays: Insights from the FRANCE-PCI registry

Frontiers in Cardiovascular Medicine, section Coronary Artery Disease


Conclusions

Indirect admission to PCI for STEMI is associated with 1-year mortality independent of FMC to balloon time and should be considered as an indicator of quality of care. Indirect admission is associated with higher-risk features and suboptimal antithrombotic therapy. Older age, paramedics-FMC and self-presentation to a private physician were independently associated with indirect admission. Our study, supports population education especially targeting elderly, more adequately dispatched FMC and improved pre-CCL management.

Clinical impact of FFR-guided PCI compared to angio-guided PCI from the France PCI registry

Catheterization and Cardiovascular Interventions


Conclusions

FFR‐guided PCI improves outcome at 1 year compared to angio‐guided PCI with a reduction of 64% of death.



2021

X-Ray, false friend of the interventional cardiologist - Risks, evaluation, quality improvement - Status report from France-PCI registry

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 435-445


Abstract

Although indispensable, radiation exposure during cardiac catheterization procedures can cause specific radiation-induced diseases. These affect the patient but also the interventional cardiologist. Exposure to high or repeated radiation doses causes deterministic effects. Moreover, even low dose exposure, especially when repeated, produces a risk of stochastic effets. In that respect, it is crucial to improve the radiation safety of cardiac angiography and interventions, to promote radiation protection and to maintain this exposure « As Low As Reasonably Achievable » (...)

Incresead exposure to X-Ray during coronary angiography and percutaneous coronary interventions associated with fractionnal flow reserve measurement and endocoronary imaging techniques

Radiation Protection Dosimetry, March 2021


Conclusions

Increased patient exposure associated with FFR and intracoronary imaging is moderate in diagnostic coronary angiography and minimal or none in PCI, provided optimization techniques are used. It should not be a limitation on the use of these techniques given the important additional information they provide.

Focus on high speed rotational atherectomy by Rotablator in 2021 and datas from France PCI registry

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 435-445


Abstract

Developed in the late 1980s, rotational atherectomy has raised a lot of hope for its innovative principle of selective ablation, allowing volume reduction (instead of redistribution) of atherosclerotic plaque, while sparing healthy tissue. Long shunned for its disappointing results on restenosis, the Rotablator finally reasserted itself in the 2000s; era of drug eluting stents and coronary angioplasty boom, thus generating emergence of complex lesions. Indeed, the Rotablator has demonstrated an undeniable benefit in complex (type C) and calcified lesions preparation (before stenting), with a procedural success rate of 95%. (...)

Is coronary multivessel disease in acute myocardial infarction patients still associated with worse clinical outcomes at 1-year?

Clin Cardiol. January 2021


Conclusions

MultiVessel Disease (MVD) still represents an important proportion of STEMI patients but their prognoses were not associated with worse clinical outcomes at 1-year compared with one-VD patients in a modern reperfusion area and secondary medication prevention.

Stent thrombosis : a won battle ? (data from the France PCI registry)

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 388-394


Conclusions

Since 2014, the incidence of ST at 1 year has been decreasing but remains stuck at a floor level of 0.54% in 2019. The battle for ST seems to have been partly won and its risk factors well identified, but its mortality is still high.


2020

Incidence, delays, and outcomes of STEMI during COVID-19 outbreak : Analysis from the France PCI registry

JACEP October 2020


Conclusions

According to the multicenter France PCI registry, the COVID-19 outbreak in France was associated with a significant decline in STEMI undergoing PPCI and longer transfer time for patients who presented directly to the ED. Mortality rates doubled, but the difference was not statistically significant.

Where have the STEMIs gone during COVID-19 lockdown ?

Eur Heart J Quality of Care and Clinical Outcomes. April 2020


The coronavirus disease 2019 (COVID19) outbreak has threatened to over whelm European   healthcare systems, potentially overshadowing other emergencies including ST-segment elevation myocardial infarction (STEMI).


2019

Does helicopter transport delay prehospital transfer for STEMI patients in rural areas ? Findings from the CRAC France PCI registry.

Eur Heart J Acute Cardiovasc Care. 2019 Aug 31


Conclusions

Helicopter transport of STEMI patients was five times less effective than ground transport in maintaining the 90-minute first medical contact to primary percutaneous coronary intervention time recommended in guidelines, particularly for transfer distances less than 50 km.

 


2018

Factors associated with delay in transfer of patients with ST-segment elevation myocardial infarction from first medical contact to catheterization laboratory : Lessons from CRAC, a French prospective multicentre registry.

Arch Cardiovasc Dis. 2019 Jan;112(1):3-11.


Conclusions

In ST-segment elevation myocardial infarction, a transfer time from first medi-cal contact to primary percutaneous coronary intervention of > 120 min was associated withgeographic, systemic and comorbid factors, several of which appear reasonably actionable.


 

Non-ST elevation acute coronary syndrome: CRAC register experience.

Ann Cardiol Angeiol (Paris). 2018 Dec;67(6):422-428


Conclusions

Nonagenarians with a positive-troponin non-ST elevation ACS have more severe coronary artery disease and a poorer prognosis than those younger than 90 years of age

 

The CRAC cohort model: A computerized low cost registry of interventional cardiology with daily update and long-term follow-up

Rev Epidemiol Sante Publique. 2018 May ; 66(3):209-216


Conclusions

This integrated computerized IC registry led to the construction of an exhaustive, reliable and costless database, including all coronary patients entering in participating IC centers in the CVL region. This solution will be developed in other French regions, setting up a national IC database for coronary patients in 2020: France PCI


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