Impact of cardiac rehabilitation and treatment compliance afterST-segment elevation myocardialinfarction (STEMI) in France, the STOP SCA+ study

Frontiers in Cardiovascular Medicine, June 2025

Conclusions

This study showed that patients admitted for emergency revascularization at the acute phase of a STEMI mainly had favorable outcomes at 1 year, with few complications or death. Pejorative outcomes appeared to be related to patients’characteristics, initial clinical presentation, and access to rehabilitation care, whereas no impact could be observed fornon-compliance. Matching two complementary clinical and medico-administrative databases proved to be reliable for assessing outcomes on a large scale. This permanent and multicentric database with systematic long-term follow-up in ICC provides excellent quality data and immediate feedback at a largescale, without high cost nor changing usual practice due to a fully integrated electronic medical report. This large reliable database could soon provide care quality improvement linked to benchmarking and promote robust studies

Impact of P2Y12 inhibitors pretreatment on stent thrombosis in patients undergoing percutaneous coronary intervention: insight France PCI registry

Canadian Journal of Cardiology 2025 Oct 29 

Conclusions 

In this large real-world cohort, P2Y12 inhibitors pretreatment was associated with a significant reduction in in-hospital stent thrombosis and improved one-year clinical outcomes without increasing major bleeding risk. These findings suggest that selective use of antiplatelet pretreatment may still play a crucial role in improving ischemic outcomes for patients undergoing PCI.

Safety and efficacy of NOAC vs.VKA in patients treated by PCI: a retrospective study of the FRANCE PCI registry

Frontiers in Cardiovascular Medicine, January 2024

Conclusions

NOAC seems to have a better efficacy and safety profile than VKA. However, potential indication bias were found.

The France PCI registry: Design, methodology and key findings *

Archives of Cardiovascular Disease, September 2023

Conclusions 

This fully electronic, daily updated, high-quality, low-cost, national registry is sustainable, and is now expanding. Merging with medicoeconomic databases and nested randomized scientific studies are ongoing steps to expand its scientific potential.

*Publication soutenue par le Groupe Athérome coronaire et Cardiologie Interventionnelle (GACI)

Is the duration of dual antiplatelet therapy (DAPT) excessive in post-angioplasty in chronic coronary syndrome ? Data from the France-PCI registry (2014-2019)*

Frontier in CV medecine, March 2023

Conclusions

Post-PCI DAPT duration in CCS was higher than international recommendations in the France PCI registry between 2014 and 2019. More than half of the angioplasty performed for CCS are followed by a DAPT > 12 months. Ischemic risk assessment influences the duration of DAPT. This risk is probably overestimated nowadays, leading to a prolongation of DAPT beyond the recommended durations, thus increasing the bleeding risk.

*Publication soutenue par le Groupe Athérome coronaire et Cardiologie Interventionnelle (GACI)

Prevalence, management and outcomes of percutaneous coronary intervention for coronary in-stent restenosis: Insights from the France PCI Registry

Cardiovascular Revascularization Medicine, February 2023

Conclusions

In a large all-comers registry, in-stent restenosis (ISR) PCI was not infrequent and associated with worse prognosis than non-ISR PCI. Further studies and technical improvements are warranted to improve the outcomes of ISR PCI

X-Ray, false friend of the interventional cardiologist - Risks, evaluation, quality improvement - Status report from France-PCI registry

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 435-445

Abstract

Although indispensable, radiation exposure during cardiac catheterization procedures can cause specific radiation-induced diseases. These affect the patient but also the interventional cardiologist. Exposure to high or repeated radiation doses causes deterministic effects. Moreover, even low dose exposure, especially when repeated, produces a risk of stochastic effets. In that respect, it is crucial to improve the radiation safety of cardiac angiography and interventions, to promote radiation protection and to maintain this exposure « As Low As Reasonably Achievable » (...)

Focus on high speed rotational atherectomy by Rotablator in 2021 and datas from France PCI registry

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 435-445

Abstract

Developed in the late 1980s, rotational atherectomy has raised a lot of hope for its innovative principle of selective ablation, allowing volume reduction (instead of redistribution) of atherosclerotic plaque, while sparing healthy tissue. Long shunned for its disappointing results on restenosis, the Rotablator finally reasserted itself in the 2000s; era of drug eluting stents and coronary angioplasty boom, thus generating emergence of complex lesions. Indeed, the Rotablator has demonstrated an undeniable benefit in complex (type C) and calcified lesions preparation (before stenting), with a procedural success rate of 95%. (...)

Is coronary multivessel disease in acute myocardial infarction patients still associated with worse clinical outcomes at 1-year?

Clin Cardiol. January 2021

Conclusions

MultiVessel Disease (MVD) still represents an important proportion of STEMI patients but their prognoses were not associated with worse clinical outcomes at 1-year compared with one-VD patients in a modern reperfusion area and secondary medication prevention.

Stent thrombosis : a won battle ? (data from the France PCI registry)

Ann Cardiol Angeiol (Paris). 2021 Dec;70 : 388-394

Conclusions

Since 2014, the incidence of ST at 1 year has been decreasing but remains stuck at a floor level of 0.54% in 2019. The battle for ST seems to have been partly won and its risk factors well identified, but its mortality is still high.

Incidence, delays, and outcomes of STEMI during COVID-19 outbreak : Analysis from the France PCI registry

JACEP October 2020

Conclusions

According to the multicenter France PCI registry, the COVID-19 outbreak in France was associated with a significant decline in STEMI undergoing PPCI and longer transfer time for patients who presented directly to the ED. Mortality rates doubled, but the difference was not statistically significant.

Where have the STEMIs gone during COVID-19 lockdown ?

Eur Heart J Quality of Care and Clinical Outcomes. April 2020

The coronavirus disease 2019 (COVID19) outbreak has threatened to over whelm European   healthcare systems, potentially overshadowing other emergencies including ST-segment elevation myocardial infarction (STEMI).

Factors associated with delay in transfer of patients with ST-segment elevation myocardial infarction from first medical contact to catheterization laboratory : Lessons from CRAC, a French prospective multicentre registry.

Arch Cardiovasc Dis. 2019 Jan;112(1):3-11.

Conclusions

In ST-segment elevation myocardial infarction, a transfer time from first medi-cal contact to primary percutaneous coronary intervention of > 120 min was associated withgeographic, systemic and comorbid factors, several of which appear reasonably actionable.